Synonym(s): (no synonyms)
Classification (Orphanet): - Inborn errors of metabolism - Rare genetic disease - Rare renal disease - Rare skin disease Entire classification		Classification (ICD10): - Endocrine, nutritional and metabolic diseases - See
Epidemiological data: Class of prevalence: 1-9 / 1 000 000 Average age onset: adolescence / young Average age of death: - Type of inheritance: autosomal dominant		External references: 1 OMIM reference - See 1 MeSH reference: D046349
More Info - Orphanet

Gene symbol	UniProt reference	OMIM reference
CPOX	P36551	612732

- Acute abdominal pain / colic
- Autosomal dominant inheritance
- Diffuse / generalised skin hyperpigmentation / melanoderma
- Myalgia / muscular pain
- Nausea / vomiting / regurgitation / merycism / hyperemesis
- Obnubilation / coma / lethargia / desorientation
- Psychic / behavioural troubles
- Skin photosensitivity
- Thin skin
- Vesicles / bullous / exsudative lesions / bullous / cutaneous / mucosal detachment

- Constipation

- Articular / joint pain / arthralgia
- Delirium / hallucination
- Diaphragmatic palsy
- Hyponatremia